Mental Health Clinical Research

In this section you will find links to information on various clinical trials. For more information about clinical trials, please read A Participant's Guide to Mental Health Clinical Research. This is a detailed booklet from the National Institute of Mental Health. It describes what people should know before they decide to participate in a clinical trial, including a checklist of questions.

NIMH Clinical Trials

The National Institute of Mental Health supports research studies on mental health and disorders. From this link, you can participate, refer a patient or learn about results of studies.

NIH Clinical Trials

The National Institute of Health sponsors ClinicalTrials.gov, which provides regularly updated information about federally and privately supported clinical research in human volunteers in all areas. ClinicalTrials.gov gives you information about a trial's purpose, who may participate, locations, and phone numbers for more details.

NIH Clinical Center

This site offers information on clinical trials through the National Institute of Health, as well as answers to frequently asked questions about clinical trials. Professional nurses answer questions and provide information regarding the Clinical Center’s clinical research trials and associated topics. Both the general public and practicing physicians may contact the appropriate staff person for details on specific research studies and the criteria for patient referral.
To find out more, call toll free: 1-800-411-1222; TTY 1-866-411-1010.

NIDA Clinical Trials

This page from the National Institute on Drug Abuse  shows information regarding clinical trials related to chemical dependency.

University of Minnesota Clinical Trials

This page shows clinical trials in Psychiatry at the University of Minnesota, Twin Cities Campus. You can also call the department for further information at 612-273-9800.

Other research studies:

Youth Research Study Conducted at the University of Minnesota Medical School, Department of Psychiatry
This study is enrolling children and adolescents 6 to 18 years old with a parent with bipolar disorder. The study includes a diagnostic interview and biological tests including an MRI. Feedback and payment will be provided. For more information, please contact Alaa Houri at 612-273-9924.

University of Minnesota Research Study: Adaptive Treatment Study
Is your adolescent displaying symptoms of depression? Would you like him/her to participate in a treatment study that provides interpersonal psychotherapy and might include antidepressant medication? This study involves an optional MRI before and after the treatment. If your adolescent is between 12 and 17 years old, call 612-273-9845 to ask about participating in this study.

University of Minnesota Research Study: Self Harm in Young People
Adolescents between the ages of 13 and 21 who hurt themselves on purpose are being recruited to participate in a research study. Research activity options: MRI scanning and/or receiving an investigational treatment (a nutritional supplement commonly found in natural food stores). We also need healthy adolescents who do not hurt themselves for MRI scanning. All participants will be provided with feedback and will receive payment. Call 612-273-9845 to learn more.

Adolescent Depression Study, University of Minnesota Medical School, Department of Psychiatry
If you think you have depression or anxiety and are 12 to 18 years of age, you may be eligible to participate. This study includes a clinical interview, questionnaires, and physiological measurements. May include an MRI. Feedback and payment provided. For more information, please call 612-273-9924.

 

Mayo Clinic Clinical Trials

This page shows a listing of clinical trials in Brain and Nerve Disease Research at the Mayo Clinic.

 Highlighted Mayo Clinical Trial:

Prolonging Remission in Depressed Elderly (PRIDE)
 
This study will determine whether medications alone or medications and electroconvulsive therapy (ECT) work best to prevent depressive relapse and to improve quality of life for older people with severe mood disorders. For a detailed description of this study, please visit: http://clinicaltrials.gov/ct2/show/NCT01028508
 
Sponsors:   Mount Sinai School of Medicine
Collaborator:   National Institute of Mental Health (NIMH)
 
Contact:   Elizabeth Scilley    507-293-1774   scilley.elizabeth@mayo.edu 
                 Principal Investigator: Shirlene Sampson, MD
                 Rochester, Minnesota, United States, 55905

 

Additional Studies

The following are additional studies taking place in Minnesota.

  • University of MN Schizophrenia Program
    • Tobacco Use Study - Smokers with schizophrenia or schizoaffective disorder who want to quit are wanted for a research study that uses varenicline (Chantix®). To be eligible, you must smoke more than 10 cigarettes per day and be in good health. To see if you qualify, call 612-627-4840.
    • Schizophrenia Cognition Study - Does schizophrenia make it hard to focus? Plan? Remember? Difficulty with attention, memory and planning of activities are symptoms of nearly all people who have schizophrenia. These symptoms are collectively called cognitive impairment. Cognitive impairment persists despite adequate treatment of psychotic symptoms with medications for schizophrenia. Therefore, research is essential for developing medications that will minimize or alleviate cognitive impairment.
      • Volunteers must be 20 - 55 years of age and under consistent medical care; diagnosed with schizophrenia for at least two years prior to screening; and currently taking an atypical antipsychotic medication.
      • Volunteers will receive at no cost: study medication; study-related medical care; and transportation service or travel reimbursement.
      • The volunteer will need to have an identified responsible contact person (e.g., family member, social worker, case worker, or nurse) to provide support throughout the study.
        For more information about this trial, please contact the Schizophrenia Cognition Study at 612-627-4840.